Mood, stress, and mental resilience are deeply tied to physical health. Hormones, inflammation, nutrient status, blood sugar, and sleep all influence how the brain regulates emotion, which is why anxiety and depression often have physical contributors that talk therapy and medication alone may not fully address. Understanding this mind-body connection can open new avenues of support alongside traditional mental health care.

This integrative view is held by Dr. James Petros, MD, founder of NexGen Health and a physician board certified in Functional Medicine, Anti-Aging Medicine, Regenerative Medicine, Physical Medicine, and Interventional Pain Management. A Tulane University School of Medicine graduate trained at Stanford, Dr. Petros founded the practice in 2021 on the belief that true wellness is a way of life, addressing body and mind together.

How Mood Symptoms Show Up

Anxiety and depression affect the body as well as the mind, and physical symptoms are often part of the picture.

• Persistent Low Mood: sadness or loss of interest that lingers.
• Ongoing Anxiety: worry, tension, or restlessness that is hard to quiet.
• Fatigue: low energy and motivation that accompany mood changes.
• Sleep Disruption: trouble sleeping or sleeping too much.
• Brain Fog: reduced focus and clarity tied to mood.
• Physical Tension: headaches, muscle tension, or digestive upset.

The Physical Roots of Mood

Mental health is influenced by more than circumstances. Hormonal imbalances, thyroid dysfunction, chronic inflammation, nutrient deficiencies, blood sugar swings, and poor sleep can all affect mood, focus, and stress tolerance. When these factors go unaddressed, anxiety and depression can be harder to manage. Recognizing the physical contributors allows support that complements, never replaces, the care of a mental health professional.

How NexGen Health Can Help

NexGen Health provides integrative support designed to work alongside your mental health care. Care may draw on NAD IV therapy for depression, peptide therapy, IV therapy, and vitamin deficiency testing to address the body’s role in mood.

Frequently Asked Questions About Anxiety and Depression Support

Is this a replacement for therapy or medication?

No, this support complements mental health care and is designed to work alongside your therapist or physician, never to replace them.

How can physical health affect mood?

Hormones, inflammation, nutrients, blood sugar, and sleep all influence brain function, so correcting imbalances can support emotional wellbeing.

Can nutrient deficiencies affect mental health?

Yes, deficiencies in key nutrients can influence mood and energy, and correcting them often helps.

What physical factors are involved?

Thyroid, hormones, inflammation, blood sugar, and sleep are common contributors worth evaluating.

Is this approach evidence-based?

NexGen uses vetted therapies and coordinates with your existing providers as part of a complete approach.

How soon might I feel a difference?

Many people notice improvements in energy and resilience over the first weeks to months of support.

Why Choose NexGen Health

NexGen Health addresses the physical side of mental health, complementing therapy and medication. Under Dr. Petros, support is integrative, collaborative, and personalized. Located in San Jose and serving Los Gatos, Cupertino, Mountain View, and Silicon Valley, the practice helps patients care for the body behind the mind.

Support Your Wellbeing in San Jose

If you are looking for integrative support alongside your mental health care, contact NexGen Health in San Jose to schedule a consultation, call the practice, or book online.

If you are experiencing a mental health crisis or thoughts of self-harm, please contact a qualified professional or call or text 988 for immediate support.

Disclaimer: The information on this page is for educational purposes and is not a substitute for individualized medical advice, diagnosis, or treatment. Candidacy, therapies, and outcomes are determined during consultation, and individual results vary. Some therapies referenced may be provided on an off-label or investigational basis under physician supervision.